Describe lock and key mechanism of enzyme action.
Basic mechanism of enzyme catalysed reactions involves binding of active site of an enzyme with a substrate to convert it into a product. In order to explain this binding , a German chemist, Emil Fischer proposed lock and key model in 1894. This model suggests that substrate is a key and enzyme is a lock. For binding purposes, a specific substrate (key) fits into key hole (active site) of enzyme (lock).
Substrate with smaller, larger size or incorrect shape does not fit into active site of substrate.
Substrate with correct size and shape can fit into the active site of the enzyme and can get converted into product.
Basic mechanism of enzyme catalysed reactions involves binding of active site of an enzyme with a substrate to convert it into a product. In order to explain this binding , a German chemist, Emil Fischer proposed lock and key model in 1894. This model suggests that substrate is a key and enzyme is a lock. For binding purposes, a specific substrate (key) fits into key hole (active site) of enzyme (lock).
Substrate with smaller, larger size or incorrect shape does not fit into active site of substrate.
Substrate with correct size and shape can fit into the active site of the enzyme and can get converted into product.
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